Jim Mullins' Laboratory is located in the Rosen Building of South Lake Union. Our lab uses the techniques of molecular, computational, and virus biology to provide basic insights into the relationship between HIV and human hosts in an effort to fight to stop the AIDS pandemic.
We use a variety of techniques to understand the implications of HIV's extraordinary genetic diversity for the pathogenesis of AIDS and with the intention of applying this information to the development of more effective vaccines and therapies. These techniques include virology, molecular biological and statistical analysis of nucleotide sequences, and high-throughput array analysis of cellular transcription.
New Web Site! After a long time in development, our updated web site is now in place. Old content is still being integrated to our new look, but is still available via the same URLs and the site map.
2008 Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag. PLoS Comput Biol411e1000225 pubmed
2008 Evolution of CCR5 Use Before and During Coreceptor Switching. Journal of virology. Epub 2008 Sep 24 pubmed
2008 Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. Journal of virology82178548-59 pubmed
2008 Comparison of immunogen designs that optimize peptide coverage: reply to Fischer et al. PLoS computational biology41e25 pubmed
2008 Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV). AIDS research and human retroviruses244561-71 pubmed
