HIRIS aims to provide a stable, authoritative, and standardized source of data for analysing HIV-1 integration sites from the viral reservoir. It seeks to support analyses using the tools of your choice, whether that’s R and ggplot or Excel and Prism.
The data contained within comes from a variety of published sources curated by the Mullins Lab. The database itself is regularly and automatically regenerated from our primary and secondary sources in order to incorporate changes and additions.
We also maintain a private copy of HIRIS with additional, unpublished datasets from our own research and that of our collaborators. As we publish on the private datasets, they will be made available in the primary, public HIRIS database.
If you’d like to see your public HIV-1 integration site data included in HIRIS, please email us.
A few other curated datasets of viral integration sites exist. You may find that some of them better fit your needs.
See an expanded version of this plot on the Top Genes page.
Rank | Gene | # of Subjects | Unique IS | Total IS |
---|---|---|---|---|
1 | STAT5B | 10 | 21 | 41 |
2 | BACH2 | 7 | 64 | 106 |
3 | RPTOR | 7 | 9 | 10 |
4 | MKL2 | 5 | 21 | 86 |
5 | IKZF3 | 5 | 6 | 6 |
6 | NUMA1 | 5 | 5 | 6 |
7 | SAE1 | 5 | 5 | 5 |
8 | GRB2 | 5 | 5 | 5 |
9 | FKBP5 | 4 | 7 | 7 |
10 | KIAA0319L | 4 | 6 | 12 |
11 | EIF4G3 | 4 | 6 | 8 |
12 | CBFB | 4 | 6 | 6 |