Hemelaar J, Elangovan R, Yun J, Dickson-Tetteh L, Kirtley S, Gouws-Williams E, Ghys PD, WHO-UNAIDS Network for HIV Isolation and Characterisation (2020). Global and regional epidemiology of HIV-1 recombinants in 1990-2015: a systematic review and global survey. The lancet. HIV, 7(11), e772-e781. (pubmed) (doi)
Global HIV-1 genetic diversity and evolution form a major challenge to treatment and prevention efforts. An increasing number of distinct HIV-1 recombinants have been identified worldwide, but their contribution to the global epidemic is unknown. We aimed to estimate the global and regional distribution of HIV-1 recombinant forms during 1990-2015.