Mullins Molecular Retrovirology Lab

  • Department of Microbiology
  • School of Medicine
  • University of Washington
University of Washington/Fred Hutch Center for AIDS Research

Citation Information

Nakamura KJ, Heath L, Sobrera ER, Wilkinson TA, Semrau K, Kankasa C, Tobin NH, Webb NE, Lee B, Thea DM, Kuhn L, Mullins JI, Aldrovandi GM (2017). Breast milk and in utero transmission of HIV-1 select for envelope variants with unique molecular signatures. Retrovirology, 14(1), 6. (pubmed) (doi)

Abstract

Mother-to-child transmission of human immunodeficiency virus-type 1 (HIV-1) poses a serious health threat in developing countries, and adequate interventions are as yet unrealized. HIV-1 infection is frequently initiated by a single founder viral variant, but the factors that influence particular variant selection are poorly understood.

Supplemental Data

Supplemental material

Alignment of 647 sequences: Nakamura-2016.fasta

Sequence names are pipe-delimited (|) with the following fields:

  • “gb”
  • GenBank accession
  • isolate name